E Michael Lewiecki Selected Research

Postmenopausal Osteoporosis

11/2018	Abaloparatide is an Effective Treatment Option for Postmenopausal Osteoporosis: Review of the Number Needed to Treat Compared with Teriparatide.
4/2017	Proceedings of the 2016 Santa Fe Bone Symposium: New Concepts in the Management of Osteoporosis and Metabolic Bone Diseases.
1/2017	Romosozumab for the treatment of osteoporosis.
6/2016	Pharmacodynamics and pharmacokinetics of oral salmon calcitonin in the treatment of osteoporosis.
10/2014	Understanding and communicating the benefits and risks of denosumab, raloxifene, and teriparatide for the treatment of osteoporosis.
7/2012	Denosumab reduces the risk of osteoporotic fractures in postmenopausal women, particularly in those with moderate to high fracture risk as assessed with FRAX.
9/2011	New targets for intervention in the treatment of postmenopausal osteoporosis.
7/2011	Combination therapy: the Holy Grail for the treatment of postmenopausal osteoporosis?
1/2011	Safety and tolerability of denosumab for the treatment of postmenopausal osteoporosis.
12/2010	Clinical use of denosumab for the treatment for postmenopausal osteoporosis.

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E Michael Lewiecki Research Topics

Disease

100	Osteoporosis 08/2022 - 11/2002
34	Postmenopausal Osteoporosis 11/2018 - 06/2005
27	Bone Resorption 01/2019 - 06/2005
14	Metabolic Bone Diseases (Osteopenia) 04/2015 - 12/2005
10	Osteonecrosis (Kienbock's Disease) 05/2020 - 09/2008
6	Neoplasms (Cancer) 06/2016 - 10/2006
4	Hip Fractures (Intertrochanteric Fractures) 04/2020 - 06/2010
4	Bone Diseases (Bone Disease) 01/2020 - 01/2016
4	Osteoporotic Fractures 11/2018 - 07/2012
3	Femoral Fractures (Femoral Fracture) 05/2020 - 10/2016
3	Breast Neoplasms (Breast Cancer) 11/2018 - 07/2006
3	Hyperparathyroidism 08/2015 - 02/2009
3	Cellulitis 10/2014 - 12/2010
3	Rheumatoid Arthritis 07/2009 - 10/2006
2	Hypophosphatasia 01/2022 - 10/2017
2	Hypophosphatemia 01/2022 - 03/2008
2	Necrosis 10/2020 - 10/2006
2	Prostatic Neoplasms (Prostate Cancer) 11/2018 - 04/2015
2	Hypercalcemia (Milk Alkali Syndrome) 01/2017 - 10/2010
2	Vitamin D Deficiency 08/2015 - 01/2003
2	Eczema 10/2014 - 12/2010
2	Atrial Fibrillation 01/2013 - 07/2012
2	Esophageal Neoplasms (Esophageal Cancer) 01/2013 - 07/2012
2	Neoplasm Metastasis (Metastasis) 12/2009 - 07/2006
2	Infections 07/2009 - 07/2009
2	Multiple Myeloma 10/2006 - 07/2006
1	Periprosthetic Fractures 01/2022
1	Graft vs Host Disease (Graft-Versus-Host Disease) 10/2020
1	COVID-19 09/2020
1	Bone Fractures (Bone Fracture) 01/2019
1	Second Primary Neoplasms (Neoplasms, Second) 01/2016
1	Chronic Kidney Disease-Mineral and Bone Disorder (Renal Rickets) 07/2015
1	Stroke (Strokes) 10/2014
1	Venous Thromboembolism 10/2014
1	Osteoarthritis 04/2014
1	Type 2 Diabetes Mellitus (MODY) 04/2013
1	Hypertension (High Blood Pressure) 03/2013
1	Wrist Fractures 02/2013
1	Confusion (Bewilderment) 04/2011

Drug/Important Bio-Agent (IBA)

32	Denosumab FDA Link 04/2020 - 02/2006
24	Diphosphonates (Bisphosphonates)IBA 08/2022 - 11/2002
16	Monoclonal AntibodiesIBA 01/2019 - 07/2006
13	Pharmaceutical PreparationsIBA 01/2018 - 07/2006
10	romosozumabIBA 08/2020 - 01/2011
10	RANK LigandIBA 11/2018 - 07/2006
9	CalciumIBA 10/2020 - 01/2003
9	Parathyroid Hormone (Parathormone)IBA 05/2020 - 01/2012
8	Vitamin D FDA LinkGeneric 01/2022 - 07/2006
8	Zoledronic Acid (Zometa)FDA Link 05/2020 - 01/2008
8	Teriparatide (Parathar)FDA Link 11/2018 - 06/2005
8	CytokinesIBA 11/2018 - 07/2006
7	Alendronate (Alendronate Sodium)FDA LinkGeneric 01/2020 - 11/2002
6	MineralsIBA 05/2020 - 01/2006
5	Collagen Type I (Type I Collagen)IBA 01/2021 - 04/2010
5	LigandsIBA 07/2017 - 02/2009
5	Biomarkers (Surrogate Marker)IBA 01/2016 - 06/2005
4	Estrogens (Estrogen)FDA Link 01/2020 - 10/2007
4	Anabolic AgentsIBA 01/2020 - 01/2013
4	Bone Density Conservation AgentsIBA 08/2015 - 04/2009
4	Raloxifene Hydrochloride (Evista)FDA Link 10/2014 - 04/2007
4	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2011 - 07/2006
4	Ibandronic Acid (Boniva)FDA Link 04/2010 - 08/2005
3	hydroxide ionIBA 05/2020 - 09/2016
3	AndrogensIBA 11/2018 - 10/2006
3	Receptor Activator of Nuclear Factor-kappa B (TRANCE-R)IBA 09/2016 - 03/2010
3	bazedoxifeneIBA 10/2009 - 10/2007
3	Selective Estrogen Receptor Modulators (SERM)IBA 10/2009 - 10/2007
2	ProcollagenIBA 01/2021 - 06/2005
2	25-hydroxyvitamin DIBA 05/2020 - 03/2008
2	GlucocorticoidsIBA 11/2018 - 07/2004
2	Aromatase InhibitorsIBA 11/2018 - 10/2006
2	abaloparatideIBA 11/2018 - 01/2017
2	Phosphates (Orthophosphate)IBA 04/2017 - 03/2008
2	4-nitrobenzyloxyamineIBA 09/2016 - 09/2016
2	Cathepsin KIBA 09/2011 - 12/2009
2	odanacatibIBA 09/2011 - 12/2009
2	Alkaline PhosphataseIBA 04/2010 - 06/2005
2	LasofoxifeneIBA 10/2009 - 01/2009
2	Methotrexate (Mexate)FDA LinkGeneric 07/2009 - 07/2009
1	Gonadal HormonesIBA 10/2020
1	procollagen Type I N-terminal peptideIBA 05/2020
1	N- (4'- fluorobutyrophenone)- 4- (4- chlorophenyl)pyridinium (HPP(+))IBA 10/2017
1	eculizumab FDA Link 07/2017
1	Parathyroid Hormone-Related ProteinIBA 01/2017
1	salmon calcitonin (Calcimar)FDA LinkGeneric 06/2016
1	SteroidsIBA 08/2015
1	Rosiglitazone (Avandia)FDA Link 04/2013
1	Testosterone (Sustanon)FDA Link 09/2012
1	Biological ProductsIBA 04/2011

Therapy/Procedure

60	Therapeutics 08/2022 - 01/2003
4	Fracture Fixation 04/2020 - 02/2013
4	Subcutaneous Injections 01/2013 - 06/2005
3	Injections 07/2017 - 11/2007
3	Intravenous Infusions 06/2010 - 01/2008
2	Drug Therapy (Chemotherapy) 10/2020 - 10/2006
2	Duration of Therapy 01/2017 - 01/2016
2	Contraindications 10/2014 - 11/2007
1	Cell Transplantation 10/2020
1	Bariatric Surgery 01/2020
1	Orthopedic Procedures 01/2019